400-level Course Guide

HMB offers a wide variety of 400-level courses, yet how to choose which one(s) suit your interest?

Students in HMB programs entering their final year of study may be looking for a course to not only satisfy program requirements, but also expand their knowledge by taking an in-depth course on a topic of their interest.

This guide has been designed to help give further context to what these courses are about.

Please note this is not the official Calendar, and should only be used in conjunction with the Human Biology Academic Calendar. For information about pre-requisites and enrolment into these courses can be found in the Calendar and the Timetable (the 2021-2022 timtebable has not yet been releaseed). The assessment information is based on past years and can change from year-to-year.

During Balloting, students will only be able to ballot for courses that count toward their HMB program. View PDF icondetailed instructions on how to ballot.

 

THE HMB 400-LEVEL COURSE GUIDE

This course introduces life science students to biomedical advances and technologies in medicine, including drug patents, medical device implants, diagnostic and medical device software. Limitations of patent protection in commercializing medical products, and limitations to scalability may also be discussed. Specific topics vary from year to year and will be based on the course instructor's area(s) of expertise.

Prerequisite : 14 FCE complete, HMB301H1/ HMB321H1/ BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1, HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Recommended Preparation: a statistics course

Assessments to expect: essays (research based, grant proposals), group presentations, tests

Other notes: Course topics may interest students who are interested in some of the IBBME programs

HMB Programs it Counts towards: Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Term: Winter

Calendar link: HMB401H1

The bridge between basic scientific research and clinical practice integrates fundamental knowledge about molecular/cellular mechanisms and clinical disorders to increase the potential for new medical treatments, therapies and interventions as well as understanding of disease processes. Specific topics vary from year to year and will be based on the course instructor's area(s) of expertise.

Prerequisite: 14 FCE complete, BCH210H1, BIO230H1/ BIO255H1, HMB302H1/ HMB321H1/ HMB322H1/ BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1, and HMB202H1/ HMB203H1/ HMB204H1

Recommended Preparation: BCH311H1/ CSB349H1/ PSL350H1

Assessments to expect: essays (research based, grant proposal), group presentations, tests

Other notes: topics vary widely from year to year; a strong cellular-molecular background will help you in this course.

HMB Programs it Counts towards: Health & Disease, Human Biology

Term: Fall

Calendar link: HMB402H1

Since research involving human subjects lays the foundation for innovation in modern health care, this course examines health care ethics along a continuum from bench to bedside. Ethical issues are discussed in the context of specific cases involving human research, as well as contemporary clinical practice.

Prerequisite: 14 FCE complete, A HMB300-level course, HMB306H1/ PHL281H1/ other ethics course with prior approval from the unit

Assessments to expect: essays (research based), tests

Other notes: taught by a clinical ethicist; issues taken from his real-world expertise.

HMB Programs it Counts towards: Global Health, Human Biology & All HMB Specialists programs towards the bioethics requirement.

Term: Winter

Calendar link: HMB406H1

This seminar course focuses on recent research into the neurobiology underlying human behaviour. A variety of normal and abnormal human behaviours are studied which may include: voluntary action; moral cognition; hedonism; aggression; mental health; addiction; the impact of the gut microbiome on brain development and health.

Prerequisite: 14 FCE complete, HMB200H1, HMB300H1, HMB320H1/ ANA300Y1

Assessments to expect: essays (literature reviews, journal club), presentations, quizzes/tests

Other notes: topics vary widely from term to term, but brains are always involved.

Topic for 2021-2022: Brain Circuits from Physiology to Neurodegeneration

HMB Programs it Counts towards: Neuroscience

Term: Fall

Calendar link: HMB420H1

Theme based lecture and seminar course underlining current medical research in relation to the areas of genes and genetics. Topics vary yearly.

Prerequisite: 14 FCE complete, HMB265H1/ BIO260H1, HMB201H1

Recommended Preparation: HMB321H1/ BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1

Assessments to expect: essays (grant proposals), presentations

Other notes: course topics usually centre on the use of epigenetics, regeneration, and stem cell research, and there are never tests in this course.

HMB Programs it Counts towards: Fundamental Genetics & Its Applications

Term: Fall

Calendar link: HMB421H1

This course focuses on various medical research related to human disease. Topics vary based on course instructor's area(s) of expertise.

Prerequisite:14 FCE complete, PSL300H1, PSL301H1, HMB302H1/ HMB322H1, and HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: essays (research based), presentations, tests

Other notes: This course will be offered in Fall 2021 and Winter 2022 with two different topics.

Topics: 

  • Fall 2021: Mental Health in the Community - from research to policy to practice 
  • Winter 2022: Climate Change, Environmental Degradation, Displacement and Health

HMB Programs it Counts towards: Health & Disease, Human Biology

Calendar link: HMB422H1

Current research covering the breadth of neuroscience is showcased by members of the Collaborative Program in Neuroscience. Topics vary yearly, but cover the spectrum from molecular through genetic, cellular, developmental, systems, behavioural and modelling. As well, approaches to studying neurodegenerative diseases and clinical neurophysiology are introduced.

Prerequisite: 14 FCE complete, HMB200H1, CJH332H1, HMB320H1/ JHA410H1/ ANA300Y1

Assessments to expect: essays (literature review), tests

Other notes: course focuses on the analysis of the latest research in neuroscience

HMB Programs it Counts towards: Neuroscience

Term: Fall

Calendar link:HMB430H1

This course explores innovation in research and technology in the field of applied genetics. Specific topics vary from year to year and will be based on the course instructor's area(s) of expertise.

Current scientific literature pertaining to gene and genome engineering, immunotherapy and regenerative medicine will be reviewed and critically analysed in a discussion-based format. 

Prerequisite: 14 FCE complete, HMB301H1/HMB321H1/HMB360H1, HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1 (modified for 2021-2022 academic year)

Assessments to expect: essays (research based, reflections), presentations

Other notes: topics vary widely from year to year

HMB Programs it Counts towards: Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Term: Winter

Calendar link: HMB431H1

Lecture and seminar course emphasizing current research. Topics may include the digestive system, cardiovascular system, respiratory system, stem cells, and neoplasia. Topics vary depending on class interest.

Prerequisite: 14 FCE complete, HMB302H1/ HMB322H1

Recommended Preparation: BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1 Assessments to expect: essays (grant proposals), presentations

Other notes: topics tend to focus on current research in stem cell and regeneration research; HMB302H1 is the better preparation pre-requisite for this course. There are never tests in this course.

HMB Programs it Counts towards: Health & Disease, Human Biology

Term: Winter 

Calendar link: HMB432H1

Seminar and theme based course examining the opportunity to apply basic knowledge of biological determinants of disease to designing health system interventions and informatics that can have a global impact in the near term.

Prerequisite: 14 FCE complete, HMB303H1/ HMB323H1

Assessments to expect: essays (research based), presentations, tests

Other notes: This course will be offered in Fall 2021 and Winter 2022 with two different topics.

Topics: 

  • Fall 2021: Indigenous Health
  • Winter 2022: Climate Change and Human Health

HMB Programs it Counts towards: Global Health

Calendar link: HMB433H1

Introduction to complementary and alternative medical therapies. Topics include, Traditional Chinese Medicine, Naturopathy, Ayurvedic, and Mind-Body Practices. Biological mechanisms will be emphasized and therapies will be critically analyzed from an evidence-based research perspective. Integrating alternative therapies into Western practices with a focus on personalized medicine will be discussed.

Prerequisite: 14 FCE complete, BCH210H1, BIO230H1/ BIO255H1, HMB302H1/ HMB312H1/ HMB314H1/ HMB322H1/ HMB323H1/ HMB342H1, and HMB202H1/ HMB203H1/ HMB204H1

Recommended Preparation: HMB342H1/ CSB349H1/ PSL350H1/ BCH311H1

Assessments to expect: essays (literature review), poster & presentation, tests

Other notes: Course title says it all: course discussed and reviews different types of alternative therapies.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology

Term: Fall

Calendar link: HMB434H1

Theme-based lecture and seminar course underlining current basic science research in the area of molecular and cell biology, focusing on cell migration and its relevance to human health and disease. Topics may focus on the impact of fundamental processes underlying the cell biology, physiology and pathophysiology of cell motility in a variety of systems (e.g. immune, nervous system, cancer context).

Dual Delivery HyFlex model:

Lectures are live-streamed and recorded (permitting synchronous delivery, but also asynchronous attendance). Student presentations and/or exams will be synchronous (live) and delivered online during the meeting schedule, or during a final assessment period. Students need the ability to use Blackboard Collaborate and Microsoft Teams.

Prerequisite: 14 FCE complete, BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1

Assessments to expect: essays (grant proposal), group presentations, tests

Other notes: taught by a researcher who studies the biology of epithelial-mesenchymal transition (EMT) and signaling in osmotic stress and cell volume regulation.

HMB Programs it Counts towards: Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Term: Fall

Calendar link: HMB435H1

Not offered in the 2021-2022 Fall/Winter term

This lecture-based course will familiarize students with fungi of public health importance, particularly those that cause disease in humans and other animals. The course will focus on the clinical presentation, pathophysiology, and treatment of fungal infections, as well as the ecology, physiology and evolutionary biology of the agents responsible. The course will also address other ways in which fungi influence human and animal health.

Prerequisite : 14 FCE complete, HMB265H1/ BIO260H1, BIO220H1

Recommended Preparation: EEB268H1, EEB331H1/ CSB353H1

Assessments to expect: essay (peer-reviewed research article to be published on Wikipedia), tests

Other notes: Don’t let the name mislead you! This course is a fascinating mycology course– all about fungus! It is not a course for those interested in veterinary care; this is a course for students interested in fungus from a clinical research standpoint.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Calendar link: HMB436H1

This course will discuss how heavy metals are integral to organ function through various biological pathways, the importance of metal regulation and control and its relationship with gene transcription. An introduction of metallo-therapeutics will also be featured, ranging from neurodegenerative therapies to cancer treatment.

Prerequisite: 14 FCE complete, HMB265H1/ BIO260H1, BIO230H1/ BIO255H1, BCH210H1

Assessments to expect: essays (literature review), group presentations, tests

Other notes: This course is way cooler than it sounds! The biology of the human metallome opens up a field of exploration that is novel and interesting.  It integrates knowledge from Biology and Chemistry to explore how important metals like iron, copper and zinc are important for our everyday lives and bodily functions.  You'll leave the course with a whole new appreciation for metals and their role in Human Biology

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Term: Fall

Calendar link: HMB437H1

NB: This course will not be a part of the HMB Ballot process

This course, featuring a service-learning component, explores dementia. In patients with dementia, intellectual, social and occupational functioning deteriorate. The course addresses the multi-disciplinary aspects of dementia (clinical, genetic, molecular, social) with a focus on the most common cause of dementia, Alzheimer's disease.

A short application to enrol in this course is required and can be found under Special Enrolment Courses.

Prerequisite: 14 FCE complete, HMB265H1/ BIO260H1, PSL300H1, HMB300H1/ HMB302H1/ HMB320H1/ HMB321H1/ ANA300Y1

Assessments to expect: essays (grant proposal, reflections), group presentations, placement activities, tests

Other notes: This is a community engaged learning course. Students will get the opportunity to become a volunteer friendly visitor with a senior, for weekly visits to socialize and make a friend while learning about core course concepts.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, Neuroscience (HMB: Genetics students are allowed to take this course, but it does not count toward program requirements)

Term: Winter

Calendar link: HMB440H1

This advanced course aims to provide students with current, in-depth knowledge of the genetics of specific human diseases, including single gene (e.g., Huntington disease), multifactorial (e.g. Alzheimer’s disease), and non-Mendelian (e.g. mitochondrial DNA-related disease) disorders, and how the use of genetics to elucidate disease mechanisms can lead to treatments and personalized medicine in order to improve healthcare.

Prerequisite: 14 FCE complete, HMB265H1/ BIO260H1, BCH210H1, HMB302H1/ HMB321H1/ HMB322H1/ BCH311H1/ CSB349H1/ MGY311Y1/ PSL350H1, and HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Recommended Preparation: HMB321H1, PSL300H1, PSL301H1

Assessments to expect: essays (articles), lab assignments, tests

Other notes: Course focuses on the scientific underpinnings of human disease; the best preparation for this course is HMB321H1.

HMB Programs it Counts towards: Health & Disease, Human Biology, Fundamental Genetics & Its Applications

Term: Fall

Calendar link: HMB441H1

This course will not be offered in the 2021-2022 academic year.

This course focuses on current insights in brain tumour etiology and pathology as well as treatment options and side-effects. Based on a seminar format, this course is highly discussion-based and collaborative in nature.

Prerequisite: 14.0 credits complete, PSL300H1, HMB302H1/HMB322H1/HMB300H1/CJH332H1

Assessments to expect: quizzes, essays (research-based), presentations

Other notes: this course is highly interactive with a flipped-classroom style and group work – ensure you can attend in person to get the most benefit.

HMB Programs it Counts towards: Health & Disease, Human Biology, Neuroscience

Calendar link: HMB442H1

NB: This course will not be a part of the HMB Ballot process

Vitamin and mineral deficiencies, termed ‘hidden hunger,’ affect about half the world’s population. Explore the global nature, catastrophic consequences, and causes of these deficiencies. Discuss formulation and implementation of international, national, and local policies to alleviate ‘hidden hunger’ especially in infants and young children. A service-learning opportunity is integrated. Students will be required to contribute to a local community organization while using course knowledge to develop a project or initiative beneficial to the organization and community.

A short application to enrol in this course is required and can be found under Special Enrolment Courses.

Prerequisite: Completion of 14.0 credits, BIO230H1/BIO255H1, HMB302H1/ HMB303H1/ HMB312H1/ HMB314H1/ HMB322H1/ HMB323H1/ CJH332H1 (formerly CSB332H1)/ NFS382H1

Assessments to expect: essays (research based), presentations

Other notes: This is a service learning course! The final assignment includes a group presentation (recorded video or website), for the community partner; as such this work may be publicly available and used by the community partner.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, 

Term: Fall

Calendar link: HMB443H1

Proper development of the human brain is essential for human health. This course will examine how neurodevelopment failures contribute to neurological disorders and diseases, such as epilepsy and autism. Current research from basic, translational, and clinical perspectives will be examined using case studies. The impact of neurodevelopmental disorders and diseases on the individual and community will be discussed.

Prerequisite: 14 FCE complete, HMB200H1, HMB320H1/ ANA300Y1

Assessments to expect: essays (literature reviews, journal club), presentations, quizzes/tests

Other notes: This course examines how neurodevelopmental failures contribute to neurological disorders and diseases.

HMB Programs it Counts towards: Neuroscience

Term: Fall

Calendar link: HMB450H1

The bridge between basic scientific research and clinical practice integrates fundamental knowledge about molecular/cellular mechanisms and clinical disorders to increase the potential for new medical treatments, therapies and interventions as well as understanding of disease processes. Specific topics vary from year to year and will be based on the course instructor's area(s) of expertise.

Prerequisite : 14 FCE complete, HMB302H1/ HMB321H1/ HMB322H1, HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: group project (essay & presentation), tests

Other notes: topics vary widely from year to year; all about the structure and the function of the human body and how that relates to medicine.

HMB Programs it Counts towards: Health & Disease, Human Biology

Term: Winter

Calendar link: HMB452H1

Seminars explore the global AIDS crisis, adopting the medical-anthropological perspective of Paul Farmer's Infections and Inequalities. Varying epidemiological profiles of AIDS are placed in broader social, cultural, and political-economic frameworks. The impact of globalization and structural inequality on local cultures and lifestyles provides an essential backdrop to the discussions.

Prerequisite: 14 FCE complete, ANT208H1/ BIO220H1/ PHS300H1/ JNH350H1

Assessments to expect: essays (journal club), presentations

Other notes: this course is multi-disciplinary and students will study HIV/AIDS from many perspectives.Topics vary from year to year. 

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology

Term: Fall

Calendar link: HMB453H1

This seminar course focuses on recent research into the neurobiology underlying mental health issues and is highly discussion-based and collaborative in nature. Specific topics are indicated by subtopic (which may vary yearly).

Prerequisite: 14.0 credits complete, HMB200H1, HMB300H1, HMB320H1/ANA300Y1

Assessments to expect: essays (research-based), case studies, presentations

Other notes: this course is highly interactive with a flipped-classroom style and group work – ensure you can attend in person

HMB Programs it Counts towards: Neuroscience

Term: Winter

Calendar link: HMB460H1

The focus is on the theory and application of biostatistics and epidemiology to current developments in special topics in substantive areas of epidemiology (e.g., chronic disease, environmental & occupational health, infectious disease, methods, social, etc.).

Prerequisite: 14 FCE complete, HMB342H1

Assessments to expect: essays (grant proposals), presentations

Other notes: course focuses on different foci of epidemiology such as major depressive disorder, influenza, and fecal microbiota transplantation.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology

Term: Fall

Calendar link: HMB462H1

This course introduces biomechanics and builds on knowledge of the biomechanics of injury and dysfunction to develop a systematic understanding of risk, injury prevention, and initial management of injuries in sports and physical activities. Some additional topics include doping in sport, travel issues in competitive sport, and ethical issues in clinical sport medicine.

Prerequisite: 14 FCE complete, PSL300H1, PSL301H1, HMB200H1/ HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: Essays (research based), tests

Other notes: course that focuses on biomechanics of the body and injury, especially in relation to sports and physical activities.

HMB Programs it Counts towards: Health & Disease, Human Biology (note: all HMB students may take this course, but it will ONLY count toward the Health & Disease and Human Biology Programs).

Term: Winter

Calendar link: HMB470H1

Enhancing performance has broad appeal. This course explores current developments for achieving peak performance academically, physically and emotionally. We focus on the scientific basis of the links between performance and stress, and of the benefits and risks of pharmacological methods to achieve performance enhancement. Various stress management skills are introduced.

Prerequisite: 14 FCE complete, PSL300H1, HMB200H1/ HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: essays (research based, articles), group presentations (debate), tests, in course longitudinal lab like project

Other notes: The course features an individual longitudinal lab-like project that measures the effectiveness of a behavioural intervention on sleep quality and stress levels.

HMB Programs it Counts towards: Health & Disease, Human Biology, Neuroscience (note: all HMB students may take this course, but it will ONLY count toward the Health & Disease, Human Biology, and Neuroscience Programs).

Term: Fall

Calendar link: HMB471H1

Examine the physiological and biochemical responses of the human body to both acute and chronic bouts of physical activity. The impact of activity on health, and health on physical activity, is explored by examining adaptations from the cellular to the systemic level of bodily function.

Prerequisite: 14 FCE complete, PSL300H1, PSL301H1, HMB200H1/ HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: essays (research based), tests

Other notes: This course is all about physical exercise (or lack thereof) and the effects on the body. Takes a physiological and biochemical approach.

HMB Programs it Counts towards: Health & Disease, Human Biology (note: all HMB students may take this course, but it will ONLY count toward the Health & Disease and Human Biology Programs).

Term: Fall

Calendar link: HMB472H1

Dentistry is one of the oldest branches of medicine responsible for the treatment of diseases of oral cavity. This course will introduce students to the key concepts as well as the latest research in the dental sciences, including but not limited to craniofacial structures, bone physiology, odontogenesis, pathogenesis of oral diseases, and technology in dental sciences.

Prerequisite: 14 FCE complete, BIO230H1/ BIO255H1, PSL300H1, PSL301H1, HMB200H1/ HMB201H1/ HMB202H1/ HMB203H1/ HMB204H1

Assessments to expect: essays (research based), presentations, quizzes

Other notes: This course is an in-depth introduction to dental sciences from a clinical research perspective and topics include the latest research in dental sciences. This course will interest students who wish to pursue research in dentistry.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, Fundamental Genetics & Its Applications (Neuroscience students are allowed to take this course, but it does not count toward program requirements)

Term: Fall

Calendar link: HMB474H1

Building on their experience in 3rd-year labs, students participate in inquiry-based laboratory experiments in diverse areas of current human biology research. Open to students in any Human Biology program.

A short application to enrol in this course is required and can be found under Special Enrolment Courses.

Prerequisite: 14 FCE complete, HMB310H1/ HMB311H1/ HMB312H1/ HMB314H1

Assessments to expect: essays (journal club), lab assignments (bench lab- lab reports, projects, etc.)

Other notes: 

HMB Programs it Counts towards: Health & Disease, Human Biology, Fundamental Genetics & Its Applications (note: all HMB students may take this course, but it will ONLY count toward the Health & Disease, Human Biology, and HMB: Genetics Programs).

Term: Winter

Calendar link: HMB489H1

NB: This course will not be a part of the HMB Ballot process

An experiential learning course exploring health-related challenges and social determinants of health in partnership with local community organizations. Lectures and tutorials will support learning of selected biological and social aspects of health and disease, neuroscience, genetics or population health, and the development of scientific knowledge translation skills relevant to the community agencies.

A short application to enrol in this course is required and can be found under Special Enrolment Courses.

Prerequisite: BIO230H1/ BIO255H1, HMB265H1/ BIO260H1, BCH210H1, PSL300H1, PSL301H1, HMB200H1/ HMB201H1/ HMB202H1/ HMB203H1/HMB204H1

Exclusion: HMB473H1

Assessments to expect: essays (research based, reflections), placement activities, poster & presentation, tests

Other notes: This is a community engaged learning course. Students will serve community organizations in a volunteer capacity on a weekly basis and collaborate with them for project/research work.

HMB Programs it Counts towards: Global Health, Health & Disease, Human Biology, Neuroscience

Calendar link: HMB490Y1

NB: This course will not be a part of the HMB Ballot process

This course introduces students to complex issues at the interface between environment and health where health is broadly defined. Each year a current and controversial case study is explored from scientific, medical, political and policy perspectives. The course takes students from the molecular to individual to population and societal levels.

Prerequisite : 14 FCE complete, ENV341H1/ HMB302H1/ HMB312H1/ HMB314H1/ HMB322H1

Assessments to expect: essays (grant proposal), presentations

Other notes: Course teaches you to write grant proposals and focuses on the environmental effects on human health.

HMB Programs it Counts towards: Health & Disease, Human Biology

Calendar link: JEH455H1

This course focuses on the use of neuroimaging techniques in understanding how trauma, disorders, and disease impact neural structure and function. Lectures will focus on local and long-range neural impact of pathology and neuroimaging assessment. Lab work will focus on practical skills including image processing, analyses, and experimental design.

Prerequisite: 9 FCE complete, PSL300H1, BIO230H1, HMB200H1/ PSY290H1/ ANA300Y1

Recommended Preparation: HMB320H1

Assessments to expect: lab assignments (computer lab), tests

Other notes: students will be introduced to and learn MRI, EEG, and MEG

HMB Programs it Counts towards: Neuroscience

Term: Winter

Calendar link: JHA410H1